WARNING: Estrogens have been reported to increase the chance of womb (endometrial) cancer, especially in women who receive estrogen-only hormone therapy. Estrogens may also increase the risk of cancer of the ovary. Estrogen-containing products should not be used to prevent heart disease or dementia. Estrogen used alone or in combination with another hormone (progestin) can increase the risk for heart disease (including heart attacks), stroke, serious blood clots in the lung (pulmonary embolism) or leg (deep venous thrombosis), cancer of the breast, or dementia. These risks appear to depend on the length of time this medicine is used and the amount of estrogen per dose. Therefore, this medicine should be used for the shortest possible length of time at the lowest effective dose, so you obtain the benefits and minimize the chance of serious side effects from long-term treatment. Consult your doctor or pharmacist for details. Some medicines or medical conditions may interact with this medicine. INFORM YOUR DOCTOR OR PHARMACIST of all prescription and over-the-counter medicine that you are taking. ADDITIONAL MONITORING OF YOUR DOSE OR CONDITION may be needed if you are taking corticosteroids (such as prednisone), seizure medicines (such as phenytoin, carbamazepine, or phenobarbital), "blood thinners" (such as warfarin), certain antifungal medicines (such as ketoconazole or itraconazole), macrolide antibiotics (such as clarithromycin or erythromycin), cimetidine, rifampin, ritonavir, tacrine, or St. John's wort. DO NOT START OR STOP ANY MEDICINE without doctor or pharmacist approval. Inform your doctor of any other medical conditions including any personal or family history of cancer, breast lumps, clotting problems, womb problems (such as uterine fibroids or endometriosis), heart disease (such as high blood pressure, heart attacks, or congestive heart failure), stroke, diabetes, cholesterol/lipid problems, gallbladder problems, low thyroid hormone (hypothyroidism), high blood pressure during pregnancy (toxemia), yellowing of the eyes/skin (cholestatic jaundice) during pregnancy or with past estrogen use, depression, asthma, seizures, migraine headaches, kidney problems, abnormal calcium level in the blood, lupus, growths on the liver, history of tobacco use, excessive weight gain, allergies, pregnancy, or breast-feeding. USE OF THIS MEDICINE IS NOT RECOMMENDED if you have a history of undiagnosed or abnormal vaginal bleeding, certain types of cancers (such as breast cancer), estrogen-dependent growths, history of blood clots or clotting problems, liver problems, certain blood disorders (porphyria), active/recent (within the past year) stroke or heart attack. Contact your doctor or pharmacist if you have any questions or concerns about taking this medicine.