WARNING: This medicine decreases the action of the immune system. This may increase your risk of infection. It may also increase your risk for developing certain types of cancer (eg, lymphoma, skin cancer). Tell your doctor right away if you notice signs of infection (eg, fever, chills, persistent sore throat) or any changes in the appearance or size of a mole, night sweats, unusual growths or lumps, or unusual tiredness or weakness. Some medicines or medical conditions may interact with this medicine. INFORM YOUR DOCTOR OR PHARMACIST of all prescription and over-the-counter medicine that you are taking. DO NOT TAKE THIS MEDICINE if you have taken cyclosporine within the last 24 hours. DO NOT TAKE THIS MEDICINE if you are taking asenapine, cisapride, citalopram, a potassium-sparing diuretic (eg, spironolactone), mifepristone, streptogramins (eg, dalfopristin, quinupristin), or ziprasidone. ADDITIONAL MONITORING OF YOUR DOSE OR CONDITION may be needed if you are taking other medicine to suppress your immune system, a medicine that may increase the risk of a certain type of irregular heartbeat (QT prolongation), or other prescription or nonprescription medicines (eg, used for birth control, cancer, infections, inflammation, aches and pains, heartburn or reflux, hepatitis, high blood pressure, high cholesterol, HIV infection, hormone replacement therapy, Huntington disease, immune system suppression, irregular heartbeat or other heart problems, mental or mood problems, nausea or vomiting, pain, Parkinson disease, seizures, stomach or bowel problems, ulcers), multivitamin products, or herbal or dietary supplements (eg, herbal teas, coenzyme Q10, garlic, ginseng, ginkgo, St. John's wort). Ask your doctor or pharmacist if you are unsure if any of your medicines may increase the risk of QT prolongation or might interact with this medicine. DO NOT START OR STOP any medicine without doctor or pharmacist approval. Inform your doctor of any other medical conditions, including diabetes or high blood sugar, high blood potassium levels, high blood pressure, a weakened immune system, any type of infection, allergies, pregnancy, or breast-feeding. TELL YOUR DOCTOR if you have a history of chronic (long-term) infection; a certain type of anemia (pure red cell aplasia); heart, kidney, or liver problems; or skin cancer . TELL YOUR DOCTOR if you have recently received or will be receiving a live vaccine (eg, measles, mumps), if you will be in close contact with anyone who has received a live vaccine, or if a member of your family has had skin cancer. Contact your doctor or pharmacist if you have any questions or concerns about using this medicine.