WARNING: THIS MEDICINE CONTAINS A NONSTEROIDAL ANTI-INFLAMMATORY DRUG (NSAID). It may cause an increased risk of serious and sometimes fatal heart and blood vessel problems (eg, heart attack, stroke). The risk may be greater if you already have heart problems or if you take this medicine for a long time. Do not use this medicine right before or after bypass heart surgery. THIS MEDICINE MAY CAUSE AN INCREASED RISK of serious and sometimes fatal stomach or bowel ulcers and bleeding. Elderly patients may be at greater risk. This may occur without warning signs. Some medicines or medical conditions may interact with this medicine. INFORM YOUR DOCTOR OR PHARMACIST of all prescription and over-the-counter medicine that you are taking. DO NOT TAKE THIS MEDICINE if you are also taking dasatinib. ADDITIONAL MONITORING OF YOUR DOSE OR CONDITION may be needed if you are taking angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril), anticoagulants (eg, warfarin), antiplatelet medicines (eg, clopidogrel), aspirin, bisphosphonates (eg, alendronate), corticosteroids (eg, prednisone), cyclosporine, dabigatran, desirudin, diuretics (eg, furosemide, hydrochlorothiazide), heparin, itraconazole, ketoconazole, lithium, low molecular weight heparins (LMWHs) (eg, enoxaparin), methotrexate, other NSAIDs (eg, naproxen), probenecid, quinolones (eg, ciprofloxacin), salicylates (eg, aspirin), rivaroxaban, or selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine). DO NOT START OR STOP any medicine without doctor or pharmacist approval. Inform your doctor of any other medical conditions, including a history of kidney or liver problems, diabetes, stomach or bowel problems (eg, bleeding, perforation, ulcers, inflammation), swelling or fluid buildup, a connective tissue disease (eg, lupus), asthma, growths in the nose (nasal polyps), mouth inflammation, alcohol abuse, allergies, pregnancy, or breast-feeding. Tell your doctor if you drink alcohol or smoke, or if you have poor health, dehydration or low blood volume, swelling or fluid retention, or low blood sodium levels. Tell your doctor if you have high blood pressure, blood disorders, bleeding or clotting problems, heart problems (eg, heart failure), or blood vessel disease, or if you are at risk for any of these diseases. USE OF THIS MEDICINE IS NOT RECOMMENDED if you have had an asthma attack or a severe allergic reaction (eg, severe rash, hives, trouble breathing, growths in the nose, dizziness) after taking aspirin or an NSAID (eg, naproxen, celecoxib). USE OF THIS MEDICINE IS NOT RECOMMENDED if you are 30 weeks pregnant or more, if you have moderate to severe kidney problems, or if you have recently had or will be having bypass heart surgery. Contact your doctor if you have any questions about taking this medicine.