Differin Coupon & Discounts

Save on Differin at your pharmacy with the free discount below.

Differin is a prescription topical acne medication that has been proven effective in the treatment of acne vulgaris. Differin can cost as much as $500 per tube, but luckily there are ways to reduce the price. A simple way to save money on this medication is to print our free Differin coupons to present in your local pharmacy and save up to 75% off the price. Also sign up for a Differin discount card from FamilyWize and continue to save each time you refill your medication. Follow the link below to claim your Differin coupon now, or get more information about this medication below.

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About Differin

What is Differin?

Differin is a topical acne treatment for acne vulgaris. Differin contains adapalene, a third-generation retinoid. Retinoids are very effective at treating acne as they help the skin to extrude comedones and prevent new ones from forming. Comedones are the dead skin cells and sebum that combine to block the pores of the skin, resulting in inflammation and irritation. The efficacy of adapalene is comparable to that of other retinoids like tretinoin but with fewer side effects. Retinoids can cause redness, dryness, and irritation of the skin in treated areas, but adapalene seems to cause less of this irritation.

How do I take Differin?

To reduce the Differin retail price, use our Differin coupons or a savings card when you buy your medication in your local pharmacy. Differin comes as a tube of gel or cream to be applied topically. Differin should only be applied to clean, dry skin. Apply a pea-sized amount to the affected areas and gently rub it in once daily in the evenings unless otherwise specified by your doctor. Wash your hands after each application. Use a non-comedogenic moisturizer about 30 minutes after application to reduce irritation. Avoid sun exposure while undergoing treatment with retinoid medications. If your condition doesn’t show improvement within 12 weeks, consult with your doctor.

What if I forget to take a dose of Differin?

If you miss an application of Differin, apply it as soon as you remember. If it’s almost time for you next dose, skip the missed dose and continue on your regular schedule. Do not apply two doses at once to try to catch up. If you are considering applying Differin in the morning because you missed a dose, be sure to avoid sun exposure.

What happens if I overdose on Differin?

Overdose on Differin is not likely. Excessive use will result in severe skin irritation. If you or someone you know accidently ingests Differin, contact the Poison Control Center at 1-800-222-1222.

Before taking Differin, tell your doctor if:

  • You are using any other acne or topical medications on the affected area.

  • You are allergic to any of the ingredients in this medication.

  • You must spend a lot of time outdoors or in the sun.

  • You have dermatitis, eczema, or another skin condition besides acne.

  • You are pregnant or breastfeeding.

What are the possible side effects of taking Differin?

Possible side effects from using Differin include dry, red, itchy, scaly skin during the first few weeks of treatment and possibly a burning or stinging sensation upon application. Sun exposure may increase these side effects.

How do I store Differin?

Store Differin in its original container at a room temperature between 68 and 77 degrees Fahrenheit. Keep your medication out of reach of children.


Use caution when using other skin care products such as shaving cream, lotions, or astringents that may contain alcohol and cause further drying and irritation of the skin.

Brand Names

Other brand names similar to Differin include Epiduo, which also contains benzoyl peroxide. The generic name for Differin is adapalene. To get a discount on Differin, use our free coupons to get up to 75% off the price when you fill your prescription. Also sign up for a free Differin discount card from FamilyWize and continue to save on every refill.


“I have been able to afford and purchase my prescribed medications for prices much better than using my insurance. I am trying to understand how that is possible. Anyway, I highly recommend”

- Sarah Proctor - Austin, TX

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