WARNING: Antidepressants may increase the risk of suicidal thoughts or actions in children, teenagers, and young adults. However, depression and certain other mental problems may also increase the risk of suicide. Talk with the patient's doctor to be sure that the benefits of using this medicine outweigh the risks. Families and caregivers must closely watch patients who take this medicine. It is important to keep in close contact with the patient's doctor. Tell the doctor right away if the patient has symptoms like worsened depression, suicidal thoughts, or changes in behavior. Discuss any questions with the patient's doctor. Some medicines or medical conditions may interact with this medicine. INFORM YOUR DOCTOR OR PHARMACIST of all prescription and over-the-counter medicine that you are taking. DO NOT TAKE THIS MEDICINE if you are taking a fenfluramine derivative (eg, dexfenfluramine), nefazodone, sibutramine, tramadol, or tryptophan. DO NOT TAKE THIS MEDICINE if you are taking or have taken linezolid, a monoamine oxidase inhibitor (MAOI) (eg, phenelzine), selegiline, or St. John's wort within the last 14 days. ADDITIONAL MONITORING OF YOUR DOSE OR CONDITION may be needed if you are taking certain diet medicines (eg, phentermine), lithium, metoclopramide, rasagiline, selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine), serotonin and norepinephrine reuptake inhibitors (SNRIs) (eg, duloxetine), serotonin 5-HT1 receptor agonists (eg, sumatriptan), trazodone, tricyclic antidepressants (eg, amitriptyline), anticoagulants (eg, warfarin), aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen), diuretics (eg, furosemide, hydrochlorothiazide), azole antifungals (eg, ketoconazole), cimetidine, cyproheptadine, aripiprazole, clozapine, haloperidol, phenothiazines (eg, chlorpromazine, thioridazine), risperidone, metoprolol, or a medicine that contains methylene blue. DO NOT START OR STOP any medicine without doctor or pharmacist approval. Inform your doctor of any other medical conditions, including a history of seizures, heart problems (eg, heart failure, irregular heartbeat), abnormal electrocardiogram (ECG), recent heart attack, high blood pressure, high cholesterol, overactive thyroid, liver problems, lung problems, kidney problems, stomach or bowel bleeding, blood or bleeding problems, increased eye pressure (eg, glaucoma), nervous system problems, metabolism problems, allergies, pregnancy, or breast feeding. TELL YOUR DOCTOR if you or a family member has a history of bipolar disorder (manic-depression), other mental or mood problems, suicidal thoughts or attempts, or alcohol or substance abuse. TELL YOUR DOCTOR if you are dehydrated, have low blood sodium levels, or drink alcohol. Tell your doctor if you will be having electroconvulsive therapy (ECT). Contact your doctor or pharmacist if you have questions or concerns about using this medicine.