WARNING: Antidepressants may increase the risk of suicidal thoughts or actions in children, teenagers, and young adults. However, depression and certain other mental problems may also increase the risk of suicide. Talk with the patient's doctor to be sure that the benefits of using this medicine outweigh the risks. Families and caregivers must closely watch patients who take this medicine. It is important to keep in close contact with the patient's doctor. Tell the doctor right away if the patient has symptoms like worsened depression, suicidal thoughts, or changes in behavior. Discuss any questions with the patient's doctor. SOME MEDICINES MAY INTERACT with this medicine. DO NOT TAKE THIS MEDICINE IF you are taking sodium oxybate (GHB) or tryptophan. Do not take this medicine if you are taking or have taken linezolid, methylene blue, or a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the past 14 days. TELL YOUR HEALTH CARE PROVIDER if you are taking any other medicines, especially any of the following: anticoagulants (eg, warfarin), aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen), antipsychotics (eg, olanzapine, haloperidol), phenothiazines (eg, thioridazine), selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine), serotonin-norepinephrine reuptake inhibitors (SNRIs) (eg, duloxetine, venlafaxine), "triptans" (eg, sumatriptan), diuretics (eg, furosemide, hydrochlorothiazide), azole antifungals (eg, itraconazole, ketoconazole), delavirdine, HIV protease inhibitors (eg, indinavir, ritonavir), carbamazepine, amiodarone, barbiturates (eg, phenobarbital), buspirone, digoxin, hydantoins (eg, phenytoin), nefazodone, or medicine for high blood pressure. This may not be a complete list of all interactions that may occur. Ask your health care provider if this medicine may interact with other medicines you take. DO NOT START OR STOP any medicine without doctor or pharmacist approval. Inform your doctor of any other medical conditions, including irregular heartbeat (eg, long QT syndrome) or other heart problems, low blood pressure, liver problems, kidney problems, blood electrolyte problems (eg, low blood sodium, potassium, or magnesium levels), sickle cell anemia, multiple myeloma, leukemia, dehydration, a deformed penis (eg, angulation, cavernosal fibrosis, Peyronie disease), allergies, pregnancy, or breast-feeding. Tell your doctor if you or a family member has a history of bipolar disorder (manic-depression), other mental or mood problems (eg, depression), suicidal thoughts or attempts, or alcohol or substance abuse. Tell your doctor if you drink alcohol, are scheduled to have surgery, or if you have a history of a heart attack. This medicine should not be used in CHILDREN or TEENAGERS; safety and effectiveness in children and teenagers have not been confirmed. Children and teenagers may also be more sensitive to its effects, especially the increased risk of suicidal thoughts or actions. Contact your doctor or pharmacist if you have any questions or concerns about using this medicine.