Odefsey Coupon & Discounts

Save on Odefsey at your pharmacy with the free discount below.

Odefsey is an antiviral medication that is used in the treatment of HIV. Odefsey prices for a thirty-tablet supply start at $2300 and rise to about $2800, depending on the vendor. For those who do not have an Odefsey copay card, coupons are available from FamilyWize that can lower Odefsey costs by as much as 75% at local pharmacies. To download, print, or email yours, click the ‘Claim Discount’ button on the Odefsey page, and then present your coupon every time you fill a prescription.

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About Odefsey

What is Odefsey?

Odefsey is a combination of three antiviral medications, emtricitabine, rilpivirine, and tenofovir prescribed to treat HIV or to help prevent those with a high risk for HIV from contracting it. It may also help to decrease the risk of developing AIDS or HIV-related illnesses. The three medications are nucleoside and nucleotide reverse transcriptase inhibitors (NRTIs) that work by slowing the spread of HIV through the body.

How do I take Odefsey?

The Odefsey drug is dispensed as a tablet that is taken orally once a day, with water and usually with a meal. Follow the dosing instructions exactly and continue to take this medication even if you feel well. Odefsey does not cure HIV.

What if I forget to take a dose of Odefsey?

If you forget to take your scheduled dose of Odefsey, do so as soon as you remember and are able unless more than 12 hours have passed since the usual dosing time. In this instance, skip the missed dose and resume the regular schedule. Do not increase the number of pills taken or change the regimen to make up for a missed dose.

What happens if I overdose on Odefsey?

If an overdose of the Odefsey drug is suspected, contact the Poison Control Center at 1-800-222-1222. If the individual has stopped breathing or lost consciousness, contact Emergency Services at 911.

Before taking Odefsey, tell your doctor if:

  • You are allergic to emtricitabine, rilpivirine, tenofovir, or any of the ingredients in the Odefsey tablet

  • You are pregnant, planning a pregnancy, or are nursing a child

  • You are taking any medications, vitamins, or supplements

  • You have liver or kidney disease

  • You have hepatitis

  • You have osteoporosis or other bone diseases

  • You have tuberculosis

  • You have cytomegalovirus

  • You have a history of depression or other mental disorders

What are the possible side effects of taking Odefsey?

Side effects, both mild and severe, have been reported by people who have taken Odefsey. Minor side effects include sleep difficulties, a mild rash, diarrhea, headaches, change in skin color or tone, unusual dreams, or burning, pain, or tingling of the hands or feet. If any of these conditions persist or worsen, seek medical help. Serious life-threatening side effects have also been reported including lactic acidosis, liver damage, allergic reactions to the medications Odefsey contains, bone pain, changes in urination or urine color, muscle weakness or pain, fever, sores on the mouth, body blisters, pink and swollen eyes, or signs of jaundice or a liver infection. Contact your doctor immediately if you experience any of these.

How do I store Odefsey?

Keep Odefsey tightly sealed in its original container, out of the reach of children and away from heat, moisture, and light. Dispose of any expired or unused doses according to the instructions of your doctor or pharmacist.


Odefsey may cause life-threatening lactic acidosis or liver damage. Contact your doctor if you become pregnant while taking Odefsey; do not breastfeed while taking this medication. Odefsey may cause changes in mood or behavior including depression and suicidal thoughts; do not drive, operate heavy machinery or equipment, use power tools, or handle firearms or explosives until its effects are known. Do not use this medication to treat hepatitis B.

Brand Names

Odefsey is a brand name for a specific combination of anti-viral medications prescribed to treat HIV; this combination is also available under the brand name Complera. However, these medications cannot be substituted for each other as the ratios of the active medications may be different. To help control Odefsey costs, price-reducing coupons are available on the FamilyWize website that lower prices by as much as 75% at area pharmacies.


“I have been able to afford and purchase my prescribed medications for prices much better than using my insurance. I am trying to understand how that is possible. Anyway, I highly recommend”

- Sarah Proctor - Austin, TX

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