WARNING: This medicine may cause fetal harm (eg, birth defects) or fetal death. DO NOT take this medicine if you are pregnant or if you may become pregnant and are not using an effective form of birth control. You must make sure you are not pregnant before you start this medicine. DO NOT become pregnant while you take this medicine or for as long as any medicine remains in your body after you stop treatment. This medicine may stay in the body for 2 years or longer after you stop it. Women who may become pregnant must use effective birth control while they take this medicine and for as long as any medicine remains in the body. AFTER YOU STOP THIS MEDICINE, your doctor may prescribe other medicines to help remove this medicine from your body more quickly. Blood tests may also be performed to check if any medicine remains in the body. Talk with your doctor for more information and if you have questions about effective birth control. SERIOUS AND SOMETIMES FATAL LIVER PROBLEMS have been reported with this medicine. Your doctor will monitor your liver function while you use this medicine to check for liver problems. Do not take this medicine if you have liver problems or if you have abnormal liver function tests before taking this medicine. Ask your doctor if you are taking other medicines that may harm the liver. Contact your doctor right away if you develop symptoms of liver problems, such as dark urine, pale stools, yellowing of the skin or eyes, stomach pain, severe or persistent nausea or loss of appetite, or unusual tiredness. Some medicines or medical conditions may interact with this medicine. INFORM YOUR DOCTOR OR PHARMACIST of all prescription and over-the-counter medicine that you are taking. ADDITIONAL MONITORING OF YOUR DOSE OR CONDITION may be needed if you are taking rifampin, anticoagulants (eg, warfarin), cholestyramine, medicines that may harm the liver (eg, acetaminophen, ketoconazole, isoniazid, certain medicines for HIV infection), or medicines that may cause nerve problems. Tell your doctor if you are currently taking or have recently taken methotrexate or another medicine that may suppress your immune system. Ask your doctor if you are unsure if any of your medicines might harm the liver, may suppress the immune system, or may cause nerve problems. DO NOT receive a live vaccine (eg, measles, mumps) while you are taking this medicine. Talk with your doctor before you receive any vaccine. Tell your doctor if you are taking medicine to treat or prevent malaria, or if you are taking another medicine to treat rheumatoid arthritis. DO NOT START OR STOP any medicine without doctor or pharmacist approval. Inform your doctor of any other medical conditions, including a weakened immune system, an infection, if you drink alcoholic beverages, allergies, pregnancy, or breast-feeding. Tell your doctor if you have a history of lung problems, tuberculosis (TB) or a positive TB test, high blood pressure, blood or bone marrow problems, diabetes, liver problems, abnormal liver function tests, an infection that keeps coming back, or you have recently received a vaccination. Tell your doctor if you have or have a history of kidney problems or you are on dialysis. USE OF THIS MEDICINE IS NOT RECOMMENDED if you have bone marrow problems; a severely weakened immune system; a severe, uncontrolled infection; liver problems (eg, hepatic insufficiency or failure); abnormal liver function tests prior to taking this medicine; or a history of hepatitis B or C infection. USE OF THIS MEDICINE IS NOT RECOMMENDED if you are pregnant, planning to become pregnant, or breast-feeding, or if you may become pregnant and are not using effective birth control. Contact your doctor or pharmacist if you have any questions or concerns about taking this medicine.